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Zoltan Machaty

Animal Sciences 

  • Professor of Animal Sciences
CRTN Room 2058
270 S. Russell Street
West Lafayette, IN 47907-2041

Area of Expertise: Reproductive Physiology and Developmental Biology

Education: B.S., Debrecen University, Hungary; M.S. and Ph.D., Szent Istvan University, Hungary
Post-doctoral Training: University of Missouri, Columbia, Missouri
Sabbatical: Cardiff University, Cardiff, United Kingdom, 2012

Research Program


ANSC 53400 - Advanced Reproductive Physiology

Animal Sciences Graduate Programs Committee Chair

News Releases

Cellular Clues - Animal Sciences researchers look for links between egg quality and disease development - Purdue Agricultures Magazine, Summer 2007

Personal Information

Dr. Machaty grew up in Hungary. He has a wife, two daughters, and a cat. He enjoys travelling, hiking, and photography. Zoltan can bake excellent bread. 


L-R photos: Pig embryo after DNA staining | Pig egg | Pig blastocysts

Awards & Honors

(2015) Honorary Professor. University of West Hungary.


Machaty, Z. Complete Activation of Mammalian Oocytes. U.S. Patent No. US 6,211,429 B1. Washington, D.C.: U.S. Patent and Trademark Office.

Selected Publications

Wang, C., Lee, K., Gajdocsi, E., Bali Papp, A., & Machaty, Z. (2012). Orai1 mediates store-operated Ca2+ entry during fertilization in mammalian oocytes. Developmental Biology, 365, 414-423.

Lee, K., Wang, C., & Machaty, Z. (2012). STIM1 is required for Ca2+ signaling during mammalian fertilization. Developmental Biology, 367, 154-162.

Gonzalez-Garcia, J., Bradley, J., Nomikos, M., Paul, L., Machaty, Z., Lai, F., & Swann, K. (2014). The dynamics of MAPK inactivation at fertilization in mouse eggs. J. Cell Sci, 127(Pt 12), 2749-2760.

Machaty, Z., & Wang, C. (2013). Calcium influx in mammalian eggs. Reproduction, 145, 97-105. Retrieved from http://www.reproduction-online.org/content/145/4/R97.long

Wang, C., & Lee, K. (2012). Store-Operated Ca2+ Entry in Germ Cells: Role in Egg Activation. In Store-operated Ca2+ entry (SOCE) pathways. Wien, Austria: Springer-Verlag GmbH.

Herrick, J., Wang, C., & Machaty, Z. (in press). Selection of permeating cryoprotectants for vitrification of in vitro matured feline oocytes. Reprod. Fertil. Dev.

Lee, K., Wang, C., Spate, L., Murphy, C., Prather, R., & Machaty, Z. (2014). Gynogenetic activation of porcine oocytes. Cell. Reprogram, 16, 121-129.

Machaty, Z. (2013). Oocyte calcium homeostasis. In Oocyte physiology and development in domestic animals (1, 145-164). Hoboken, NJ: Wiley-Blackwell.

Gonzalez-Garcia, J., Machaty, Z., Lai, F., & Swann, K. (2013). The dynamics of PKC-induced phosphorylation triggered by Ca2+ oscillations in mouse eggs. Journal of Cellular Physiology, 228, 110-119. Retrieved from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746124/

Department of Animal Sciences, 270 S Russell Street, West Lafayette, IN 47907 USA, (765) 494-4808

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