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Zoltan Machaty

Animal Sciences 

  • Associate Professor of Animal Sciences
LILY Room 3-233
915 W. State St.
West Lafayette, IN 47907-2054

Area of Expertise: Reproductive Physiology and Developmental Biology

Education: B.S., Debrecen University, Hungary; M.S. and Ph.D., Szent Istvan University, Hungary
Post-doctoral Training: University of Missouri, Columbia, Missouri

Research Program


ANSC 53400 - Advanced Reproductive Physiology 

News Releases

Cellular Clues - Animal Sciences researchers look for links between egg quality and disease development - Purdue Agricultures Magazine, Summer 2007

Awards & Honors

(2010) David C. Pfendler Outstanding Counselor Award. Purdue University.


Machaty, Z. (2001). Complete Activation of Mammalian Oocytes. U.S. Patent No. US 6,211,429 B1. Washington, D.C.: U.S. Patent and Trademark Office.

Selected Publications

Machaty, Z. (2013). Signal transduction during fertilization in pig oocytes with special regard on gene preservation. 2nd Fatty Pig Science and Utilization International Conference, 13.

Lee, K., Wang, C., Spate, L., Murphy, C. L., Prather, R. S., & Machaty, Z. (in press). Gynogenetic activation of porcine oocytes. Cellular Reprogramming.

Gonzalez-Garcia, J. R., Machaty, Z., Lai, F. A., & Swann, K. (2013). The dynamics of PKC-induced phosphorylation triggered by Ca2+ oscillations in mouse eggs. Journal of Cellular Physiology, 228, 110-119.. Retrieved from

Machaty, Z. (2013). Oocyte calcium homeostasis. In Oocyte physiology and development in domestic animals (Vol. 1, pp. 145-164). Hoboken, NJ: Wiley-Blackwell.

Gonzalez-Garcia, R., Bradley, J., Machaty, Z., Paul, L., Nomikos, M., Lai, F. A., & Swann, K. (2013). The dynamics of Mos and MAPK inactivation during fertilization of mouse eggs. Proc. Gordon Research Conference on Fertilization and Activation of Development, 48.

Machaty, Z., & Wang, C. (2013). Calcium influx in mammalian eggs. Reproduction, 145, 97-105. Retrieved from

Wang, C., Lee, K., Gajdocsi, E., Bali Papp, A., & Machaty, Z. (2012). Orai1 mediates store-operated Ca2+ entry during fertilization in mammalian oocytes. Developmental Biology, 365, 414-423.

Lee, K., Wang, C., & Machaty, Z. (2012). STIM1 is required for Ca2+ signaling during mammalian fertilization. Developmental Biology, 367, 154-162.

Tippmann, K., Wang, C., Jaeger, L. A., & Machaty, Z. (2012). Evidence of store-operated calcium entry in porcine cumulus cells. Proc. 4th Annual Illinois Symposium on Reproductive Sciences, 84.

Wang, C., Jaeger, L. A., & Machaty, Z. (2012). Physical trafficking of the endoplasmic reticulum to the plasma membrane is required for store-operated Ca2+ entry in porcine oocytes. Proc. 4th Illinois Symposium on Reproductive Sciences, 75.